High dose medroxyprogesterone, rates of bone resorption, and changes in spinal bone density.

Depot Medroxyprogesterone Acetate and Bone Density

The 2002 National Survey of Family Growth reported that 5.3% of all US women aged 15 through 44 currently using contraception used DMPA.1 Among contraceptors, 13.9% of those aged 15 to 19 and 10.1% of those aged 20 to 24 currently used DMPA compared with 1.6% of those aged 40 to 44.1 Decreasing rates of adolescent pregnancy between 1995 and 2002 are considered to be due in part to increased use...

Depot medroxyprogesterone and bone mineral density.

OBJECTIVE To investigate depot medroxyprogesterone (DMPA)-associated bone loss in a general practice setting. DESIGN Forty-eight patients from a single practice who had used DMPA for contraception for more than 2 years. All patients had a serum oestradiol and if the serum level was <52 pmol/l or >52 pmol/l with menopausal symptoms, bone mineral densitometry (BMD) measurements were made at the...

Evaluation of sticky bone efficacy to reconstruction of human jaw bone resorption and defects: case report

Background: One of the most significant factors in the success of dental implant procedures, can be mentioned by the quality and quantity of jaw bone. The occurrence of some problems such as trauma, infection, pathological lesions and the long-term absence of teeth in patients, it causes irregularities in the jaw bone and can get bone resorption. Sever defects after trauma or tumor resection ne...

Medroxyprogesterone acetate (Depo-Provera) and bone mineral density loss.

Changes in bone after high-dose irradiation. Biomechanics and histomorphology.

We studied the effects of high-dose irradiation on the mechanical properties and morphology of cortical bone in rabbits for 52 weeks after a single dose of 50 Gy of electron-beam to the tibia. After four weeks, the bending strength of the irradiated bone was unchanged, but at 12 weeks, the strength had decreased significantly. At 24 weeks after irradiation mean strength was less than half of co...